After Mewtwo fully matures and awakens from a long slumber in a laboratory on New Island, he learns of his origin as Mew's clone from Dr. Fuji. Infuriated that Fuji and his colleagues see him as nothing more than an experiment, he unleashes his psychic powers and destroys the laboratory. Giovanni, witnessing the carnage afar, approaches and convinces Mewtwo to work with him to hone his powers. However, after Mewtwo learns of his purpose to be a weapon for Giovanni's benefit, he escapes back to New Island where he plots revenge against humanity.
